The cost of a cycle depends on the total milligrams the titration scheme consumes, not on the price of an isolated vial. Using the escalation scheme employed in clinical trials, twelve weeks total between 50 and 70 mg, which in the September 2026 catalogue corresponds to a range of $1.180.000 to $1.610.000.
How much does a 12-week tirzepatide cycle cost in Colombia?
Using the titration scheme employed in clinical trials, twelve weeks total 60 mg, corresponding exactly to one 60 mg vial. In the September 2026 catalogue that vial costs $1.180.000, with VAT included and free shipping.
That equals $98.333 per week and $19.667 per milligram. More conservative or broader schemes change the figure, detailed in the scenarios table.
How are cycle milligrams calculated?
The calculation is arithmetic. The weekly dose of each titration block is multiplied by the number of weeks in the block, and the results are summed. Four-week titration blocks were used in the obesity trial programme, where the dose was increased stepwise from 2.5 mg.(1)
| Weeks | Weekly dose | Block milligrams |
|---|---|---|
| 1 to 4 | 2.5 mg | 10 mg |
| 5 to 8 | 5 mg | 20 mg |
| 9 to 12 | 7.5 mg | 30 mg |
| Total | — | 60 mg |
The match between the standard scheme total and the 60 mg presentation is why that vial is the lowest-cost option for a cycle of this length.
What does each titration scenario cost?
Three schemes cover the usual range described in the literature. The cost column corresponds to the cheapest vial combination in the catalogue covering the required milligrams.
| Scenario | Titration | Total mg | Vials | Cost | Per week |
|---|---|---|---|---|---|
| Conservative | 2.5 mg × 4 wk, then 5 mg × 8 wk | 50 mg | 1 × 60 mg | $1.180.000 | $98.333 |
| Standard | 2.5 / 5 / 7.5 mg, four weeks each | 60 mg | 1 × 60 mg | $1.180.000 | $98.333 |
| Broad escalation | 2.5 / 5 / 10 mg, four weeks each | 70 mg | 1 × 60 mg + 1 × 10 mg | $1.610.000 | $134.167 |
In the conservative scenario, 10 mg of the 60 mg vial remain unused. Acquiring exactly 50 mg via a 30 mg vial plus a 20 mg vial would cost $1.480.000, that is $300.000 more than the single 60 mg vial. It is a direct example of why the larger presentation is cheaper even when it exceeds the requirement.
Why does price per milligram change across presentations?
Because fixed costs associated with the vial, lyophilisation, packaging and shipping are spread across more milligrams in a larger presentation.
| Presentation | Price | Price per mg | Difference vs 60 mg |
|---|---|---|---|
| 10 mg vial | $430.000 | $43.000 | +119% |
| 20 mg vial | $690.000 | $34.500 | +75% |
| 30 mg vial | $790.000 | $26.333 | +34% |
| 60 mg vial | $1.180.000 | $19.667 | reference |
The difference between the extremes exceeds twofold. A buyer comparing only vial prices across suppliers with different presentations reaches a wrong conclusion systematically. The full table by compound is on the price per milligram page.
What does the price include?
- ✓Complete kit: lyophilised vial, bacteriostatic water, preparation guide and suggested protocol.
- ✓VAT included and electronic invoice.
- ✓Free shipping nationwide in Colombia.
- ✓Batch verification: origin certificate of analysis and destination counter-verification.
Limits of this calculation
Considerations
- The calculation is arithmetic over milligrams and catalogue prices. It does not constitute a dosing recommendation or a protocol.
- The titration schemes cited come from clinical trial design and are used here purely as a computational basis.
- Research-grade tirzepatide holds no INVIMA registration and is not intended for medical, diagnostic or therapeutic use.
- Prices correspond to the September 2026 catalogue and may change.
References
- Jastreboff AM, Aronne LJ, Ahmad NN, et al. Tirzepatide Once Weekly for the Treatment of Obesity. N Engl J Med. 2022;387(3):205-216. DOI: 10.1056/NEJMoa2206038. ClinicalTrials.gov: NCT04184622.
- Frías JP, Davies MJ, Rosenstock J, et al. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. N Engl J Med. 2021;385(6):503-515. DOI: 10.1056/NEJMoa2107519.
